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348 VisualSonics Vevo 2100 Imaging System Operator Manual Rev 1.1
Chapter 47: Acquiring Contrast Mode images
Contrast agent technology
Contrast Mode imaging requires the use of contrast agents. Contrast agents are
gas-filled microbubbles that produce a strong echogenic signal when excited with
an ultrasound pulse.
VisualSonics provides a family of contrast agent kits for targeted and non-
targeted applications.
Non-targeted contrast agents
Non-targeted contrast agents are injected into the vascular system either via a
small bolus or a continuous infusion using a syringe pump.
The contrast agents are free flowing in the vascular system for a period of time
until they are either destroyed with a high-powered ultrasound sequence or are
cleared through the system via the kidney or the liver.
Targeted contrast agents
Targeted contrast agents are microbubbles similar to those used in untargeted
applications, but are conjugated with a ligand that will bind to specific molecular
markers.
A targeted contrast agent flows freely through the vascular system until it finds
the specific receptor. At this time it binds to the molecular marker on the
endothelial surface of the vessel and will no longer flow freely.
An ultrasound image of a region with bound contrast agents displays the strong
echogenic signal provided by the contrast agent.
Displaying contrast agents as an overlay
Before you begin
Acquire your contrast data:
Typical Contrast Mode image acquisition session (page 338)
Typical Contrast 3D-Mode image acquisition session (page 341)
f To display the contrast data as an overlay using the control panel:
1. In a cine loop acquired by using the
Image Sequence
process, drag the right
side range control bracket to the end of the cine loop.
- VisualSonics 1
- 2100 Imaging System 1
- Contents 3
- Managing operator access 60 4
- Acquiring image data 100 5
- Analyzing image data 156 7
- Appendixes 365 11
- Glossary of Terms 444 12
- Index 448 12
- Getting started 13
- Introduction 14
- Monospace 15
- System description 16
- MicroScan™ transducer 19
- Transducer options 20
- Front panel 21
- Rear panel 21
- Control panel 23
- Grab bars 24
- Transducer and gel holder 24
- Castors 24
- Air filters 25
- Network connection 26
- Display monitor 26
- Speakers 27
- Isolation transformer 27
- Available configurations 29
- Quick Start Tutorial 30
- 17. Press 32
- 19. Click Export 32
- Vevo fundamentals 33
- Chapter 4 34
- To turn your system ON: 35
- To turn your system OFF: 35
- Application packages 36
- Operators 36
- Studies, series and images 37
- Image acquisition modes 37
- B-Mode overview 37
- M-Mode overview 38
- Color Doppler Mode overview 38
- 3D-Mode overview 39
- Power Doppler Mode overview 39
- Contrast Mode overview 39
- Logging on 41
- Chapter 5: Logging on 42
- Chapter 5: Logging on 43
- Mode window workspace 44
- Mode window 45
- Left panel workspace 47
- To open your Study Browser: 49
- Preferences window workspace 51
- To open the Copy To window: 54
- Export window 55
- Vevo Imaging Station 58
- Managing operator access 60
- Chapter 9 61
- Adding an administrator 62
- Adding a standard operator 63
- Modifying an operator 64
- Deleting an operator 65
- Changing the active operator 67
- Section 4 69
- General preferences 70
- Cine Loop Size preferences 71
- Auto SAVE preferences 72
- Image Export preferences 73
- PW Doppler Scale preferences 73
- Contrast Mode preferences 74
- 3. Click OK 75
- Preference Description 76
- Physiological Alarm Levels 77
- Chapter 11 79
- Chapter 12 80
- Blood Pressure 84
- Degrees 84
- Chapter 13 88
- Annotations preferences 89
- Command Description 90
- Transducer preferences 91
- Applications preferences 92
- Preset Settings section 96
- Monitor preferences 97
- Systems Log preferences 97
- Upgrade preferences 98
- 6. In the Upgrade box: 99
- Acquiring image data 100
- Working with transducers 101
- Storing the transducer 102
- Quick release mount 103
- Quick release post 103
- 3D motor connector 103
- 3D motor 104
- Transducer 104
- Chapter 17 107
- Save Preset 108
- Physiological data sources 109
- Physio Settings 110
- 2. Press 111
- Physiological Range section 112
- Blood Pressure section 113
- Respiration Gating section 115
- Respiration trace (yellow) 116
- ECG Trigger section 117
- To set the ECG triggering: 118
- 7. Press 119
- Saving image data 122
- Saving an image frame 123
- Scan/Freeze 124
- Cine Store 124
- Cine Loop Review 124
- Frame Store 124
- Section 6 125
- Chapter 21 126
- Working with studies 127
- Finding a study 129
- Owner Read-only 130
- Locking a study 131
- Working with series 132
- Study Info 133
- Closing an active series 134
- Deleting a series 135
- Opening an image 136
- Labeling an image 136
- Storing an image 137
- Chapter 25 139
- High Highest resolution 141
- Study Management 142
- 8. Click OK 144
- 9. Click OK 144
- Header text Header text 146
- 1. Press 147
- To copy a study: 152
- Chapter 26 152
- Importing studies 154
- 5. Click OK 155
- Analyzing image data 156
- Vevo Imaging Workstation 157
- Working with cine loops 158
- Cine loop review controls 159
- To use this dial control: 160
- Creating cine loops 161
- Measurement basics 164
- Area Description 165
- Generic measurements 166
- Protocol measurements 167
- Adding protocol measurements 168
- Measurement units 169
- Working with measurements 170
- Adding embryo measurements 172
- M-Mode measurement chains 173
- Deleting measurements 174
- Working with annotations 175
- Predefined annotations 176
- Cardiac Package annotations 177
- Category Annotation text 178
- Vascular Package annotations 180
- Adding annotations 180
- Modifying annotations 181
- To delete an annotation: 182
- To show/hide annotations: 182
- Creating an analysis report 184
- 3. Click Report 185
- Exporting an analysis report 188
- B-Mode imaging and analysis 189
- Acquiring B-Mode images 190
- B-Mode window workspace 192
- Screen Keys 193
- Mode Settings 193
- Image Width 194
- Display Map 194
- Image Depth 195
- Transmit Power 196
- Depth Offset 196
- Line Density 196
- Dynamic Range 197
- B-Mode acquisition settings 198
- Adding focal zones 199
- Analyzing B-Mode images 202
- Traced distance measurement 203
- 2D Area measurement 203
- Angle measurement 204
- Modifying the LV area trace 207
- To modify a contour: 207
- Time Interval measurement 208
- Lens radius measurement 210
- To create the LV wall trace: 213
- Contour 219
- Orbit line 219
- VevoStrain 220
- To view strain data in 3D: 223
- M-Mode imaging and analysis 224
- Acquiring M-Mode images 225
- M-Mode window workspace 227
- Sweep Speed 228
- Frequency 230
- Focal Zones 230
- M-Mode acquisition settings 233
- 3. Adjust the 234
- Analyzing M-Mode images 235
- Velocity measurement 236
- Heart rate measurement 236
- To trace the inner LV walls 237
- Section 10 245
- Doppler Mode images 246
- Surface blockout zone 249
- Distance blockout zone 249
- Doppler Gain 253
- Baseline 253
- Beam Angle 253
- Velocity 254
- Wall Filter 254
- Doppler Angle 255
- Parameter Description 256
- MHz. Adjust with the 256
- To set your PW Doppler SV: 258
- Chapter 38 260
- Single point measurement 266
- Option Description 268
- Related information 269
- 3D-Mode imaging and analysis 272
- How 3D-Mode works 273
- Acquiring 3D-Mode images 275
- 6. Press 276
- 8. Press Scan 277
- 3D-Mode window workspace 279
- Command Description 280
- Command Step size 280
- Orienting the transducer 286
- Analyzing 3D-Mode images 288
- Rotating an image 290
- Panning an image 290
- Rendering a 3D image 291
- Sculpting an image 293
- Rotational segmentation 296
- 3D Volume 1 -- 001 if 297
- Parallel segmentation 298
- Editing a volume contour 300
- To move a contour: 301
- Linear distance measurement 302
- Section 12 304
- Chapter 43 305
- Priority 308
- Sensitivity 313
- Display 314
- Section 13 320
- Chapter 45 321
- Section 14 337
- Chapter 47 338
- To create the reference set: 340
- Tool Description 345
- Pre Trigger 346
- Image Sequence 346
- Contrast agent technology 348
- Non-targeted contrast agents 348
- Targeted contrast agents 348
- Setting Description 350
- Contrast region measurement 356
- To copy and paste a region: 357
- Chart Y Axis 359
- Chart X Axis 359
- Calculation 359
- Display Options 359
- Chart Y Axis 360
- Cardiac region measurement 361
- Direction Description 362
- Appendixes 365
- Liver protocol 366
- Spleen protocol 367
- Gallbladder protocol 368
- Kidney protocol 368
- Adrenal Glands protocol 369
- Pancreas protocol 370
- Female Reproductive protocol 370
- Mammary Gland protocol 371
- Male Reproductive protocol 371
- Cardiac Measurement Package 372
- PSLAX protocol 372
- Calculation definitions 373
- SAX protocol 374
- LV MASS protocol 375
- ARCH protocol 376
- Simpson's protocol 377
- Volume/Flow protocol 378
- AoV Flow protocol 379
- AoV VTI, Mean Velocity 380
- MV Flow protocol 381
- TV Flow protocol 382
- PV Flow protocol 383
- Tissue Doppler protocol 384
- Uterine Horn protocol 385
- Placenta protocol 386
- Ophthalmology protocol 386
- Vascular Measurement Package 387
- Mesenteric Arteries protocol 387
- Carotid Arteries protocol 389
- Measurement definitions 391
- Iliac Arteries protocol 393
- Femoral Arteries protocol 395
- Saphenous Arteries protocol 396
- Renal Arteries protocol 397
- Other Artery measurements 398
- Umbilical Arteries protocol 399
- Troubleshooting 401
- PW Doppler Mode 402
- 3D-Mode 403
- Power Doppler Mode 403
- Contrast Mode 404
- Physiological data 404
- Appendix C 406
- Focus Depth 411
- Frame Rate 411
- L/R Screen 413
- Split Screen 417
- ---- 419
- Options and accessories 422
- Item Part number 423
- Power cords and plugs 424
- User training 425
- Supplier 426
- Appendix E 427
- Warnings 429
- Electric shock hazards 430
- Appendix F: Safety 431
- Electromagnetic interference 432
- Cautionary notes 432
- Physical hazards 432
- Magnetic field sensitivity 433
- Labeling and verification 433
- Appendix F: Safety 434
- Specifications 435
- Appendix G: Specifications 436
- Appendix H 437
- To disinfect the system: 439
- Disposal 440
- Cleaning the air filters 440
- To clean the air filter: 441
- To replace the air filter: 442
- Declaration of Conformity 443
- Glossary of Terms 444
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